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Description:
Napa® Rapid caplet is an advanced formulation of Paracetamol that contains Actizorb® technology. It dissolves up to five times faster than standard Paracetamol tablets. Napa® Rapid caplet is a fast acting and safe analgesic with marked antipyretic property. It is specially suitable for patients who, for any reason, can not tolerate aspirin or other analgesics.
Indications:
All conditions requiring relief from pain and fever such as neuritis, neuralgia, headache, earache, toothache, pain due to rheumatic disorder, cold, influenza, dysmenorrhoea, migraine, backache, pain due to arthritis etc.
Dosage and Administration:
Adults and children (aged 12 years and over): Take 1 to 2 caplets every four to six hours as needed. Do not take more than 8 caplets in 24 hours. Children (7 to 11 years): Take ½-1 caplet every four to six hours as needed. Do not take more than 4 caplets in 24 hours. Not recommended in children under 7 years.
Pregnancy and Lactation:
Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage, but patients should follow the advice of the doctor regarding its use. Paracetamol is excreted in breast milk but not in a clinically significant amount. Available published data do not contraindicate breast feeding.
Contraindications:
Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Precautions: Paracetamol should be given with care to patients with impaired kidney or liver function. Paracetamol should be given with care to patients taking other drugs that affect the liver.
Side Effects:
Side effects of Paracetamol are usually mild, including thrombocytopenia, leukopenia, breathing problem. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.
Overdosage:
Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 48 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur.
Pharmaceutical Precautions:
Keep in a cool & dry place. Protect from light. Keep out of the reach of children.
Commercial Pack:
Napa® Rapid Caplet: Box containing 270 caplets in 9×30’s blister strips. Each caplet contains Paracetamol BP 500 mg
If your delivery address is within Dhaka city, products will be delivered by within 2-5 business days. If it is outside Dhaka, it will take 5-7 business days.
Note: Product delivery duration may vary due to product availability in stock.
Pharmacology
Esomeprazole is a PPI that suppresses gastric acid secretion by inhibiting H+/K+ ATPase in the gastric parietal cell. It is the S-isomer of omeprazole. DosageTablet:
Healing of erosive esophagitis: 20 mg or 40 mg once daily for 4 to 8 Weeks. For those patients who have not healed after 4-8 weeks of treatment, an additional 4-8 weeks course of Esomeprazole may be considered.Long-term management of esophagitis: 20 mg once daily.
Symptomatic gastroesophageal reflu X disease: 20 mg once daily for 4 weeks. H. pylori eradication for treatment of duodenal ulcer: Triple therapy: 20 mg Esomeprazole once daily with 500 mg Clarithromycin twice daily, and 1 g Amoxicillin twice daily for 7-10 days.
Rabeprazole Sodium is an antiulcerant drug in the class of Proton Pump Inhibitors. Rabeprazole Sodium is a substituted benzimidazole which suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase enzyme at the secretory surface of the gastric parietal cell. It is an enteric coated tablet, because of its coated formulation it is highly stable in stomach and because of higher pKa value of Rabeprazole Sodium it provides faster onset of action. It blocks the final step of gastric acid secretion. After oral administration of 20 mg, Rabeprazole is absorbed and can be detected in plasma by 1 hour. The effects of food on the absorption of Rabeprazole have not been evaluated. Rabeprazole is 96.3% bound to human plasma proteins. Rabeprazole is primarily metabolized in the liver by Cytochrome P-450 3A (Sulphone metabolite) and 2C19 (Desmethyl Rabeprazole). Following a single 20 mg oral dose of Rabeprazole, approximately 90% of the drug is eliminated in the urine.The remainder of the dose is excreted in the feaces.
Dosage & Administration Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD): 20 mg to be taken once daily for 4 to 8 weeks. For those patients who have not healed after 8 weeks of treatment, an additional 8 week course may be considered. Maintenance of Healing of Erosive or Ulcerative Gastroesophageal Reflux Disease (GERD Maintenance): The recommended adult oral dose is 20 mg once daily. Treatment of Symptomatic Gastroesophageal Reflux Disease (GERD):The recommended adult oral dose is 20 mg once daily for 4 weeks. If symptoms do not resolve completely after 4 weeks, an additional course of treatment may be considered. Healing of Duodenal Ulcers:The recommended adult oral dose is 20 mg once daily after the morning meal for a period up to four weeks. Most patients with duodenal ulcer heal within four weeks. A few patients may require additional therapy to achieve healing. Helicobacter pylori Eradication: To Reduce the Risk of Duodenal Ulcer Recurrence- Rabeprazole Sodium 20 mg Twice Daily for 7 Days Amoxicillin 1000 mg Twice Daily for 7 Days Clarithromycin 500 mg Twice Daily for 7 Days All three medications should be taken twice daily with the morning and evening meals. It is important that patients comply with the full 7-day regimen. Treatment of Pathological Hypersecretory Conditions Including Zollinger-Ellison Syndrome: The dosage of Rabeprazole Sodium in patients with pathologic hypersecretory conditions varies with the individual patient. The recommended adult oral starting dose is 60 mg once a day. Doses should be adjusted to individual patient needs and should continue for as long as clinically indicated. Some patients may require divided doses. Doses up to 100 mg QD and 60 mg BID have been administered. Some patients with Zollinger-Ellision syndrome have been treated continuously with Rabeprazole Sodium for up to one year. Interaction Rabeprazole is metabolized by the Cytochrome P-450 (CYP-450) drug metabolizing enzyme system. Rabeprazole does not have clinically significant interactions with other drugs metabolized by the CYP-450 system,such as Warfarin and Theophylline given as single oral dose, Diazepam as a single intravenous dose, and Phenytoin given as a single intravenous dose. In normal subjects, co-administration of Rabeprazole 20 mg QD resulted in an approximately 30% decrease in the bioavailability of Ketoconazole and increase in the AUC and Cmax for digoxin of 90% and 29% respectively. Contraindications Rabeprazole Sodium is contraindicated in patient with known hypersensitivity to Rabeprazole or to any component in the product. Side Effects Rabeprazole Sodium may sometimes cause headache, diarrhoea, abdominal pain, vomiting, constipation, dry mouth, increased or decreased appetite, muscle pain, drowsiness and dizziness. Pregnancy & Lactation Rabeprazole is FDA Pregnancy Category B. No data is available on administration of Rabeprazole to pregnant women. However this drug should be used during pregnancy, only if clearly needed. There are no data on the excretion of Rabeprazole into the breast milk. A decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the benefit of the drug to the mother. Precautions Administration of Rabeprazole Sodium to patients with mild to moderate liver impairment resulted in increased exposure and decreased elimination. Caution should be exercised in patients with severe hepatic impairment. Overdose Effects There has been no experience with large overdoses with Rabeprazole. No specific antidote for Rabeprazole is known. Rabeprazole is extensively protein bound and is not readily dialyzable. In the event of overdosage, treatment should be symptomatic and supportive. Use in Special PopulationUse in pediatric patients: The safety and effectiveness of Rabeprazole in pediatric patients have not been established. Storage Conditions Store below 25°C, protected from light and moisture. Keep all medicines out of the reach of the children.
What Napa Extend is and what it is used for?
Napa® Extend is the preparation of Paracetamol 665 mg extended release formulation. It is formulated by dual granulation technology. There are two types’ granules in each tablet 31% (206 mg) is in immediate release form for immediate action and 69% (459 mg) in sustain release form for continuous pain relief for 8 hours. Paracetamol 665 mg Extended Release tablet is effective for the relief of persistent pain associated with osteoarthritis and muscle aches and pains such as backache. Paracetamol 665 mg Extended Release tablet also provides effective, temporary relief of pain and discomfort associated with headache, tension headache, period pain, toothache and pain after dental procedures, and cold & flu. Reduces fever. Before you take Napa Extend Do not take this medicine and tell your doctor if: Hypersensitivity to Paracetamol or to any of the excipients. Take special care with Napa Extend Check with your doctor before taking this medicine if: Paracetamol should be administered with caution to patients with hepatic or renal Dysfunction. Taking other medicines Anticoagulant dosage may require reduction if paracetamol medication is prolonged. Paracetamol absorption from immediate release preparations is increased by drugs which increase gastric emptying, eg metoclopramide, and decreased by drugs which decrease gastric emptying, eg propantheline, antidepressants with anticholinergic properties, narcotic analgesics. Pregnancy and Lactation Pregnancy category: B This drug should not be used during pregnancy unless the benefit outweighs the risk.A decision should be made to discontinue breastfeeding or to not administer the drug, taking into account the importance of the drug to the mother. Warnings & Precaution Hypersensitivity Reactions: Serious hypersensitivity reactions, including anaphylactic-type reactions, some of which have been life-threatening and fatal, have been reported in patients receiving Ferric Carboxymaltose. Patients may present with shock, clinically significant hypotension, loss of consciousness, and/or collapse. How to take Napa Extend Paracetamol 665 mg Extended Release tablet are to be administered orally, with or without food. Adults and children over 12 years. Two tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). The tablets must not be crushed. If you forget to take Napa Extend If you forget to take a dose, take it as soon as you remember it. If it is almost time for your next dose, do not take the missed dose. Take the next dose on time. If you stop taking Napa Extend Do not stop taking this medicine without talking to your doctor. You should not stop taking Napa Extend just because you feel better. This is because the problem may come back or get worse again. If you have any further questions on the use of this product, ask your doctor or pharmacist. Possible side effects (Adverse effect/Side effect as short form) Like all medicines, Napa Extend can cause side effects, although not everybody gets them. Reports of adverse reactions are rare. Although the following adverse reactions have been reported, a causal relationship to the administration of paracetamol has been neither confirmed nor refuted: dyspepsia, nausea, allergic and haematological reactions. How to store Napa Extend (Storage condition)?Store in a cool and dry place and keep away from children.
Tablet: Adults 1-2 tablets every 4 to 6 hours up to a maximum of 4g (8 tablets) daily. Children (6-12 years) 1/2 to 1 tablet 3 to 4 times daily. Syrup and Suspension: Children (3 months to below 1 year) 1/2 to 1 teaspoonful 3 to 4 times daily. Children (1-5 years) 1-2 teaspoonful 3 to 4 times daily. Children (6-12 years) 2-4 teaspoonful 3 to 4 times daily. Adults: 4-8 teaspoonful 3 to 4 times daily. Paediatric Drops: Children (0-3 months): 0.5 ml. Children (4 to 11 months) 1.0 ml. Children (1 to 2 years) 1.5 ml. Dose can be repeated, every 4 hours.
Suppository: Suppository should be administered rectaly. Children below (5 years) 125-250 mg, 4 times daily. Show more Preparation: Ace® Tablet: Each box contains 500 tablets in blister pack. Ace® XR Tablet: Each box contains 100 tablets in blister pack. Ace® Syrup (60 ml): 60 ml syrup in sealed cap PET bottle (with measuring cup). Ace® Syrup (100 ml): 100 ml syrup in sealed cap PET bottle (with measuring cup). Ace® Suspension: 60 ml suspension in sealed cap PET bottle. Ace® Paediatric drops (30 ml): 30 ml paediatric drop in sealed cap PET bottle (with dropper). Ace® 125 Suppository: Each box contains 20 suppositories in blister pack. Ace® 250 Suppository: Each box contains 20 suppositories in blister pack. Ace® 500 Suppository: Each box contains 20 suppositories in blister pack.
Ceevit® VITAMINS
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